SceletiumTortuosum in botany, Kanna is the most commonly used traditional herbs that work wonders for the mind-alteration. It has an impact on the evolution of human consciousness. It is naturally available, so consumers are conveniently enjoying the mood-boosting and the anxiety-reducing effects.
It is the family member of an ice plant family. Sceletium is a succulent shrub, which people are consuming for several years. The people who are living in the traditional societies of South Africa, such as Khoi and San people are using the tincture form of Sceletium for satisfying the thirst and hunger. They are also using it as a mood enhancer and for alleviating the pain.
During prehistoric times, hunters are using this plant for altering their minds. The oldest account of Sceletium usage is going back to 1662. Sceletium when fermented and dried then it becomes Kanna, which means chewy things or something to chew. People are consuming Kannaplant as it is a highly beneficial herb and safe. Kanna depression is there since the prehistoric times.
In modern times, Kannacannot only be chewed but it can also be prepared into tinctures, tea, and gel caps. Kanna can also be smoked or snuffed.
Does Kanna helpful?
According to many researchers, there are multiple modes of action when it comes to the extraction of Kanna plant. However, their major bioactive chemical compounds are called membrane alkaloids.
These mesembrine alkaloids are present in the roots and the leaves of the Kana plant and have at least nine different types. All are varying in the concentration – the typical range is in between 0.2% to 1.5%.
Side Effects of Kanna
Kanna Side effects are not well defined, but some of its alkaloids are having psychoactive properties.
When fermented, the mesembrine content of Kannais converted into Delta 7 Mesembrenone. The mesembrine alkaloids may also have the narcotic effects although of mild nature.
Researchers believe that Kanna is affecting the amygdala, the central brain region that is responsible for the processing of emotions.
Moreover, it is changing the levels of two vital proteins found in amygdala; SERT or 5-HTT the monoamine protein that transferring serotonin and enzyme called PDE4 i.e. Phosphodiesterase – 4.
Several other Kanna alkaloids are working like SRIs, which is Serotonin Reuptake Inhibitors. Thus, they are helping in stopping the serotonin from decomposing in the brain.
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